About Ledifos Ledipasvir 90 mg & Sofosbuvir 400 mg
What is Ledifos
Ledifos is a treatment for chronic hepatitis C particularly genotype 1 It is a combination of two different antiviral medicines Ledipasvir and Sofosbuvir Ledipasvir inhibits NS5A a phosphoprotein that helps with replication assembly and secretion Sofosbuvir is a nucleotide inhibitor of the viral RNA polymerase Together these drugs help prevent the spread of hepatitis C virus HCV
How is Ledifos used
Most people will be given a dose of a single pill each day for a period of 812 weeks Your doctor may prescribe you a different dosage Follow your doctors instructions
Adverse effects
Ledifos has a much better sideeffect profile than older interferonbased treatments
The most common side effects of Ledifos as reported in clinical studies are headaches tiredness and loss of appetite diarrhea insomnia and nausea
More severe side effects may display as signs of allergic reaction eg rash hives excessive itching unusual difficulty breathing tightness in your chest or swelling of the mouth face lips or tongue or cardiovascular problems If you notice any of these seek medical attention immediately and stop taking Ledifos
Warnings
Ledifos LedipasvirSofobuvir has a very high cure rate and is an ideal treatment for most hepatitis C patients There are however some situations where you should not take Ledifos
Do not take Ledifos if you have an allergy to the active ingredients ledipasvir or sofosbuvir
Do not take Ledifos if you are already taking another any other medicine that contains sofosbuvir
Do not take Ledifos if you are on any medicines that contains cobicistat elvitegravir emtricitabine tenofovir carbamazepine oxcarbazepine phenobarbital phenytoin rifabutin rifampin rifapentine rosuvastatin simeprevir St Johns wort tipranavir or ritonavir
Some other conditions should also be made known to your doctor They will not necessarily stop you from taking Ledifos but you may need to be monitored closely Advice your doctor if any of the following applies to you
if you are pregnant planning to become pregnant or are breastfeeding
if you are currently taking any prescription or nonprescription drugs herbal preparations or dietary supplements
if you are allergic to any medicines foods or other substances
if you have liver or kidney problems
If any of the above apply to you you may still be able to take Ledifos but should discuss the possibility of different treatment this with your doctor before beginning treatment
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